NUDT15 and Decreased total leukocyte count: Moreover, we present the results of a systematic review of published case reports in order to characterize dynamic changes regarding the severity of AZA-induced leukopenia in patients with NUDT15 c.415C>T homozygous or heterozygous variants alone with the purpose to provide more reference information for clinical treatment of AZA-induced myelosuppression in specific patients with only NUDT15 c.415C>T variants.