DRD2 and psychotic disorder: Indeed DRD2 is the target of the mesolimbic dopaminergic pathway projecting from the ventral tegmental area to the ventral striatum, whose dysfunction is regarded as the final common pathway for the positive symptoms of psychosis, both in the context of SCZ and BD (Schwartz et al., 1995; Kapur, 2003; Stahl, 2013; Stahl, 2018).