In contrast, the expressions of GCLC, GCLM, NQO1, and HO-1 in the liver of the model group were significantly increased by YJSB, suggesting that YJSB might improve the antioxidant capacity of the redox system in rats, reduce oxidative stress, and interfere with the development of hepatic fibrosis. This evidence concerns the gene NQO1 and Hepatic fibrosis.