OXTR and ovarian carcinoma: Meanwhile, as an evolutionary ancient and widely distributed signaling system, the OT/OTR signaling system could be utilized by many cancer types, including neuroblastoma and glioblastoma, small-cell lung carcinoma, endometrium adenocarcinoma, and ovarian carcinoma (Cassoni et al., 1998; Morita et al., 2004; Pequeux et al., 2004; Busnelli et al., 2010).