The term “antiphospholipid syndrome” (APS) refers to the correlation between antiphospholipid antibodies (aPL) [lupus anticoagulant (LA), anticardiolipin antibodies (aCL), and/or anti-2-glycoprotein-I antibodies (a2GPI)] and thrombosis and/or pregnancy morbidity1. The gene discussed is FASLG; the disease is autoimmune polyendocrinopathy.