NUMA1 and urinary bladder neoplasm: However, outcomes from large studies evaluating hematuria dipstick examination were controversial and failed to validate an effective and convincing result.11Moreover, a small number of soluble urinary protein biomarkers such as nuclear matrix protein 22, bladder tumor antigen, and cell-based tests such as UroVysion (fluorescence in situ hybridization) and ImmunoCyt have been extensively studied as potential screening methods.