BACH1 and esophageal squamous cell carcinoma: BACH1 induces epithelial-mesenchymal transition (EMT) by activating CDH2, SNAI2, and vimentin, and facilitates angiogenesis by upregulating the transcriptional activity of vascular endothelial growth factor C, thereby promoting the proliferation and metastasis of ESCC cells (Zhao et al., 2021).