For example, hemin specifically degrades BACH1 with negligible toxicity, inhibits breast cancer growth, and is used to treat patients with acute porphyria (Sun et al., 2002; Chiabrando et al., 2014; Bissell et al., 2017; Lee et al., 2019; Lignitto et al., 2019). The gene discussed is BACH1; the disease is hepatic porphyria.