The top 5 genes associated with metastasis in BLCA are FKBP6, ASIC5, MAPK8IP1, F11R, and PABPC5, while CTSV, BIRC5, SERPINA7, CST2, KLHL3 are the highest ranked genes in PAAD. The gene discussed is CTSV; the disease is pancreatic adenocarcinoma.