Another study exploring the association of different AML risk groups with KIR and HLA genotypes observed that the Cen-AB/Tel-AB combination (B content =2), activating gene KIR2DS2 and the Bw4-80I and HLA-C2 allotype, was more frequent in AML patients than in the controls (42). This evidence concerns the gene KIR3DL1 and acute myeloid leukemia.