We chose to focus on iNKT cells, based on their presence in mouse at high frequencies both in periphery (spleen) and in liver (47), as well as their contribution to severity of liver IR, as attested by decreased ALT levels, and fewer neutrophil recruitment and histological lesions in iNKT cell-deficient (Jα18KO) mice, compared to WT mice (Supplementary Figures 9, 10). The gene discussed is GPT; the disease is digestive system neoplasm.