In another ICS response study in admixed children from GALAII and SAGE cohorts with asthma, rs5995653 SNP related to apolipoprotein B mRNA-editing catalytic polypeptide 3 (APOBEC3)B and APOBEC3C genes was associated with a protective effect against asthma exacerbations (74). The gene discussed is APOB; the disease is asthma.