IGHE and asthma: The genetics of asthma can be described at three levels, (i) genetic variability that differentiates those who are more likely to develop asthma, immunogenetics, (ii) genomic variability that affects or determines how asthma patients respond to a given medication, pharmacogenomics, (iii) the genetics of asthma-related traits (i.e., lung function, asthma exacerbations, IgE levels, asthma severity).