TGFB1 and acne: As a final result in accordance with susceptibility to acne, their findings introduced a vital role for dysregulation of TGFβ-mediated signaling pathway [71]. Another genome-wide association analysis conducted by He et al. introduced two susceptible loci at 11p11.2 containing rs747650 and rs1060573 and 1q24.2 containing rs7531806.