FGF18 and colorectal carcinoma: By the construction of pUCFGF18TK vector plasmid and β-Gal enzyme linked immunosorbent assay(ELISA) assay, it was confirmed that FGF18 promoter was involved in driving reporter expression in CRC cell lines such as SW480 and HCT116 cells, compared with control group pUCTK without promoter, and cytotoxicity assay was performed.