In addition, Wei’s team further found that FGF18 could enhance the invasion of OC cells and regulate the tumor microenvironment in vitro and in vivo experiments on OC designed SKOV3 cell line and SCID mouse xenograft, especially enhance the angiogenesis of OC and enhance the infiltration and M2 polarization of tumor-associated macrophages. This evidence concerns the gene FGF18 and neoplasm.