The associated downstream targets miRNA 200c/miRNA 139 and miRNA-204/miRNA-182 were significantly down-regulated, and lncRNA H19 was also significantly correlated with FGF18, an important mediator in its regulation.Therefore, to some extent, FGF18 may be an important regulator in the process of potential diagnostic biomarkers for early GC diagnosis (46, 47). The gene discussed is H19; the disease is gastric cancer.