IL6 and colorectal carcinoma: Some of these cytokines were previously found with high plasma levels in CRC such as pro-inflammatory cytokine IL6 which is also required for Th17 differentiation (26), the pro-inflammatory MDK involved in multiple biological processes (17), and the chemoattractant of B- and T-cells CCL20 (25), whereas the detected IFNG is a well-recognized pro-inflammatory and antitumorigenic protein (31).