CXCL10 and infection: The CXCL10 chemokine is secreted by various leukocytes and tubular epithelial cells in the kidney, mainly induced by γ-interferon, a key cytokine in the inflammatory response to an allograft or infections.10, , , –14 CXCL10 can be measured in the urine, and its levels have been shown to correlate with renal allograft rejection and BK polyomavirus (BKPyV) infection in several pediatric and adult renal transplant cohorts indicating its potential as a promising noninvasive biomarker.15, , , , , , , –23