The clinical presentation of HAE Type 1/2 and nC1‐INH HAE is also similar to that of acquired recurrent angioedema without urticaria, different types of which include acquired angioedema with C1‐INH deficiency; angiotensin‐converting enzyme inhibitor (ACEi) associated acquired angioedema; and acquired idiopathic histaminergic or non‐histaminergic angioedema.6 The gene discussed is ACE; the disease is acquired angioedema.