VSX2 and microphthalmia: Our observations are also in contrast to previous reports in zebrafish using antisense oligonucleotides or morpholinos against vsx2, which show microphthalmia and optic cup malformations (Barabino et al., 1997; Clark et al., 2008; Gago-Rodrigues et al., 2015; Vitorino et al., 2009).