The enzymatic activity of Aurora B is essential for the regulatory functions of CPC (Kelly and Funabiki, 2009; Krenn and Musacchio, 2015; Meraldi et al., 2004), so Aurora B has been identified as an attractive target for cancer chemotherapy (Portella et al., 2011), with several inhibitors patented in the last decades (Jing and Chen, 2021). The gene discussed is AURKB; the disease is cancer.