In addition, TPA treatment of ILEI‐overexpressing skin lead to elevated expression of Keratin 16 (K16), a pathological marker, known to be upregulated also in psoriasis (Leigh et al, 1995; Zhang et al, 2019) as analyzed in total skin protein extracts (Fig 3D) and by qPCR on freshly sorted primary keratinocytes (Fig 3E). Here, FAM3C is linked to psoriasis.