ILEI has also been linked to other pathways: (i) the heat shock factor 1‐Calmodulin‐Akt signaling axis to regulate glucose and lipid metabolism (Chen et al, 2017) and (ii) the Ras‐MAPK pathway for EMT induction in breast cancer cell lines (Waerner et al, 2006). This evidence concerns the gene FAM3C and breast cancer.