This clinical study reported a dose‐dependent improvement in the clinically used PASI severity index (Papp et al, 2012), as well as the dose‐dependent conversion of the lesional psoriasis transcriptome to a nonlesional signature, including the validation of a strong positive correlation of K6 and K16 with the PASI score (Papp et al, 2012; Russell et al, 2014). This evidence concerns the gene KRT16 and psoriasis.