IL1B and periodontitis: Also, it was found that IL-1β, IFN-γ, and IL-17 were lower in the gingiva of mice injected with Breg cells than in those without Breg cells, confirming that Breg cells can inhibit not only the progression of the periodontitis but also regulate the T cell population,i.e., the expression levels of Th1/Th17.