Previous studies have reported that CTNND2 is a candidate gene for intellectual disability, ASD, and growth retardation of dendritic spines and synapses (Arikkath et al., 2009; Baumert et al., 2020; Belcaro et al., 2015; Hofmeister et al., 2015; Turner et al., 2015; Yuan et al., 2015). The gene discussed is CTNND2; the disease is Intellectual disability.