In this study, the authors combined all three assays: frozen lymphocyte death rate, lymphoblast mitochondrial dysfunction, and lymphoblast Target Of Rapamycin Complex 1 (TORC1) signalling which on their own were not outstanding discriminators; however, combining them gave an accuracy of 95% in determining ME/CFS patients from HC and a sensitivity of 97% and a specificity of 100% [73]. Here, CRTC1 is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.