Therefore, nanoarchitectures (ErNP@MnO2/S100A4-RGD) based on RGD-conjugation on manganese dioxide (MnO2) lanthanide nanoprobes of erbium (Er) for tumour imaging and delivering S100A4 siRNA in triple-negative breast cancer (TNBC) were developed by Ming et al. [159]. This evidence concerns the gene S100A4 and triple-negative breast carcinoma.