Meanwhile, the significant causal estimates of vWF were also observed for endometriosis of the ovary (IVW: OR = 1.34, 95%CI: 1.02–1.77, P = 0.035; WM: OR = 1.37, 95%CI: 1.03–1.81, P = 0.028) and endometriosis of the pelvic peritoneum (IVW: OR = 1.48, 95%CI: 1.11–1.97, P = 0.008; WM: OR = 1.53, 95%CI: 1.13–2.08, P = 0.006) (Fig. 4, Additional file 1: Table S8). Here, VWF is linked to medical procedure.