MTOR and hepatocellular carcinoma: while nilocitin showed a G2/M and S cell cycle arrest as a consequence of the G1 phase [99], furthermore, the flavonoid hispidulin (4’,5,7-trihydroxy-6-methoxyflavone) causes ERS-mediated apoptosis in hepatocellular carcinoma cells by stimulating the AMPK/mTOR pathway, [100].