Furthermore, the PFS forest plot showed that CKAP2L is an independent risk factor in the following cancers: ACC, KICH, KIRC, KIRP, LGG, LIHC, LUAD, MESO, PAAD, PCPG, PRAD, SARC, THCA, UCEC and UVM (Fig. 4E). The gene discussed is CKAP2L; the disease is cancer.