Focusing on individual genes, the gene embeddings clustered voltage-gated ion channel genes, such as ABCC8, ABCC9, and KCNJ11, which are targets for type 2 diabetes mellitus; JAK1, JAK2, and JAK3 kinases, which are therapeutic targets in numerous immune-related disorders; and receptor tyrosine kinases ERBB2 and ERBB3. The gene discussed is JAK3; the disease is diabetes mellitus.