PAK1 and gastric cancer: The relationship among PAXIP1-AS1, PABPC1, and PAK1 expression was also examined using western blotting and the result showed that PAXIP1-AS1 upregulation significantly decreased the expression of PAK1 (Fig. 7M), suggesting that PAXIP1-AS1 is involved in regulating PABPC1 and PAK1 expression in GC cells.