SOD3 and metabolic dysfunction-associated steatohepatitis: Because we were interested in the impact of the CCDC80 and SOD3 recombinant proteins on processes related specifically to the development of NAFLD in liver cells, we restricted the tested genes to the hepatocyte marker genes which were also DE for steatosis, fibrosis, or NASH in the KOBS liver RNA-seq DE analysis (n = 61 genes tested).