,64,76, 77, 78, 79 Additionally, new results from another group studying the UK Biobank80 support the assertion that the three SBCs CCDC80, CD300LG, and TIMP3 are secreted to serum and can be measured in serum, and that their protein levels may indicate NAFLD. This evidence concerns the gene TIMP3 and metabolic dysfunction-associated steatotic liver disease.