IL1B and dental caries: This could open new avenues for treatment plans of targeted leukotriene therapy.30 This conclusion was confirmed by previous reports.5,13 Contrasting with the results of our study,31 reported that dental caries was not significantly associated with IL-1β,interleukin-1 receptor antagonist IL-1Ra), or IL-10 concentrations in the serum and saliva of patients.