As shown in Figure 3B, Q1-LR represents the zone of early apoptotic cells (Annexin V+/PI−), and Q1-UR represents the zone of late apoptotic cells (Annexin V+/PI+) in the pseudo color plot; the proportion of apoptotic cells (Q1-LR and Q1-UR) was significantly increased after cKp and hvKp infection, compared with the PBS control group. This evidence concerns the gene ANXA5 and infection.