It has been shown that AAV patients with nephrotic hypoalbuminemia have a higher incidence of infection, end stage renal disease and all-cause mortality than patients with mild hypoalbuminemia or normal serum albumin levels.2 Ahn et al. also reported that Birmingham vasculitis activity index (BVAS) positively correlated with CRP and negatively with albumin.3 The gene discussed is ALB; the disease is stage 5 chronic kidney disease.