ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: At first, similar to the previous results observed in K562 cells and bone marrow cells from BCR-ABL gene transgenic mice, compound DBH2 at 50, 100 and 200 μg/mL concentration promoted the apoptosis of bone marrow cells from CML patients in dose-dependent manner (Fig. 4A, B).