This apparently paradoxical finding could be due to a higher suspicious of malignancy in these patients, on the basis of intra-operative clues and/or the detection of moderate-marked hypercalcemia and/or elevated PTH levels, leading to a more radical intervention, confirmed by the diagnosis of 4 PC among 5 patients who underwent PTX + TT. The gene discussed is PTH; the disease is Hypercalcemia.