TMEM173 and CHUK mRNAs were imported into the Search Tool for the retrieval of interacting genes (STRING; version 11.0; http://stringdb.org) online database for protein–protein interaction (PPI) network building to ensure their link to insulin resistance pathways and previously known genes in T2DM through STRING interaction network. The gene discussed is STING1; the disease is type 2 diabetes mellitus.