We used bioinformatics analysis to select candidate mRNA genes which are related to Type 2 DM, insulin resistance signaling, STimulator of Interferon Gene (STING), and NLR signaling pathways from public microarray databases, e.g., National Center of Biotechnology Information GEO (https://www.ncbi.nlm.nih.gov/geo/, available May 2022), Gene atlas expression database (https://www.ebi.ac.uk/gxa/home), and KEGG map (https://www.genome.jp/kegg/) to choose a pathway related to insulin resistance in T2DM and identify the target effector. Here, STING1 is linked to Insulin resistance.