TMEM173 and CHUK mRNAs, hsa-miR (-611, -5192, and -1976) miRNAs expression levels increased gradually from the control group to the pre-diabetic group to reach the highest levels in the T2DM group (p < 0.001), while RP4-605O3.4 and AC074117.2 lncRNAs expression levels decreased gradually from the control group to the pre-diabetic group to reach the lowest levels in the T2DM group (p < 0.001). This evidence concerns the gene STING1 and type 2 diabetes mellitus.