PGR and metastatic malignant neoplasm in the lymph nodes: As shown in Table 2, large vessel size remained a poor prognosis factor (p = 0.01; HR 5.6 (95% CI 1.5–21.5)) in prognostic models that also included patients’ age, tumor diameter, histological grade, lymph node metastasis, PR status, and HER2 status.