Urinary albumin excretion causes glomerular diseases, such as podocyte injury, glomerulosclerosis by mesangial hypertrophy, dysfunction of vascular endothelial cells, formation of coagulate precipitation, and epithelial casts in tubule.21 With H&E, PAS, and MT staining, we found coagulate precipitation, glomerular hypertrophy, and fibrosis in the kidney coronal section to have significantly increased at 4 weeks after nephrectomy (Figure 1, A and B, and Figure 3G); however, kidney injury was attenuated by feeding on a DHA-containing diet. This evidence concerns the gene ALB and glomerulosclerosis.