In humans, PTX3 gene polymorphisms were already described to have an impact on the susceptibility to selected infections, induced in particular by Mycobacterium tuberculosis, Pseudomonas aeruginosa and uropathogenic Escherichia coli (Chiarini et al., 2010; Jaillon et al., 2014; Olesen et al., 2007). Here, PTX3 is linked to infection.