EGFR and cancer: At the same time, pathway analysis by PANTHER Classification System revealed that these DE genes are associated with several cancer-associated signaling pathways including angiogenesis, RAS-pathway(P04393), EGFR signaling pathway (P00018), PDGF (P00047)-, FGF (P00021)-, VEGF(P00056)-, cadherin (P00012)- and integrin-signaling pathway (P00034) and glycolysis (P00024, Supplementary Figure S3B).