Consistent with the enhanced CTL expansion, the proinflammatory cytokines interleukin‐2 (Il‐2), tumor necrosis factor (Tnf)‐α, and interferon (Ifn)‐γ, which promote antitumor immune response, were found significantly enhanced in tumor tissues after G4 treatment (Figure 6E). The gene discussed is TNF; the disease is neoplasm.