After adjusting for age, general obesity, abdominal obesity, diabetes duration, hypertension, glycemic control, dyslipidemia, hyperuricemia, LH, PRL, and estradiol, the negative association between the serum FSH level and NAFLD still remained significant (OR: 0.411, 95% CI: 0.260–0.651, p < .001). The gene discussed is PLOD1; the disease is metabolic syndrome.