Subsequently, markers gene EEF1A2 and CCL5 with specificity in EEF2 + and FOLH1 + luminal subgroups were selected for immunohistochemical staining on our PCa tissue chips, and the results showed negative results in normal tissues.The positive expression of some PCa cells in the primary and lymphatic metastases suggests the existence of these two subgroups of cells in PCa (Fig. 3A). Here, FOLH1 is linked to posterior cortical atrophy.