When comparing MMP and TIMP levels in MCI patients who converted to dementia (n = 14) with MCI patients who did not convert to dementia during the follow-up period (n = 36), only TIMP-2 differed between the groups; TIMP-2 levels were higher in MCI patients who converted (77.6 ng/mL) compared to those who did not (70.3 ng/mL, P = 0.01). Here, TIMP2 is linked to dementia.