TIMP2 and Alzheimer disease: For TIMP-2 levels, post hoc comparisons revealed significantly higher levels in MCI-AD patients (72.4 ng/mL) compared to CU A− (68.1 ng/mL, F = 5.99, degrees of freedom [df] = 1, P = 0.04) and CU A+ (65.2 ng/mL, F = 9.70, df = 1, P = 0.01) controls.