Compared with controls, AF patients were more likely to experience hypertension, CHD, diabetes and had a history of statins, CCBs, β-blockers, and ACEI/ARB (p < 0.001), as well as significantly lower levels of APOAl, APOB, TG, TC, LDL-C, HDL-C, ALB, and PAB(P < 0.05), significantly higher levels of AST, SCr, and SUA(P < 0.05), but no significant difference in serum levels of Lp(a), FBG, and ALT between the two groups (P > 0.05). The gene discussed is ALB; the disease is diabetes mellitus.