Furthermore, Gal-3 serum levels could present an additional tool in order to identify high-risk patients with stable coronary heart disease, especially those patients who would benefit most from early revascularization regardless of whether it is CABG or PCI with optimization of drug therapy in order to prevent progression of the disease, either fibrosis, heart failure or the development of MACE. Here, LGALS3 is linked to coronary artery disorder.