KAT7 and gastric cancer: Furthermore, the RNA pull‐down experiment confirmed that the C2H2 domain of HBO1 (256−315 amino acids) is crucial for its interaction with circMRPS35, which recruits HBO1 into the promoter region of FOXO1/3a and increases the level of H4K5ac to inhibit the progression of GC by upregulating their transcriptional activity.250