INS and type 2 diabetes mellitus: Hayashi et al, evaluating the impact of laughter induced by a comedy show in individuals with type 2 diabetes not on insulin (16 men and 3 women, age 63.4 years, body mass index 23.5 kg/m2, glycated hemoglobin 7.2%) as compared to a usual lecture, observed that the humorous show reduced the postprandial glucose excursion by 2.5 mmol/l [44].