Gene set enrichment analysis (GSEA) and DEG analysis identified upregulation of genes involved in proliferation (MKi67, CDK1, BUB1B, CDC20), metabolism (GYS2, STC1, KIF20), adhesion (ITGA8, ICAM1, VCAN), and ECMECM(MMP9, MMP10, COL4A4) pathways in DLBCL-FRCs (Figure 4B and Supplemental Figure 5C). The gene discussed is MKI67; the disease is diffuse large B-cell lymphoma.