INS and prediabetes syndrome: Greater prediabetes consistency may indicate more severe prediabetes (inferred by the positive correlation between prediabetes consistency and fasting blood glucose) and longer duration of prediabetes Second, whereas previous studies examined older adults, we analyzed midlife women undergoing the MT, a period when insulin resistance and fracture risk accelerate.14,15 It may be easier to discern a prediabetes-fracture association during the MT because physiological changes are larger.