NOS2 and hypertensive disorder: A comprehensive treatment strategy for MS includes radical scavenging activity, as well as inhibition of key enzymes responsible for carbohydrate (α-glucosidase and α-amylase), and lipid metabolism (pancreatic lipase), hypertension [angiotensin I converting enzymes (ACE) and renin], oxidative stress [xanthine oxidase (XO)], and pro-inflammatory conditions [inducible nitric oxide synthase (iNOS)] [1].